Thank you for your question. We can ensure that you eating durian and drinking Coca-Cola at the same time do no harm to your health. Related Items FAQ More on Journey Can you use Coca-Cola to clean a toilet? Coca-Cola FAQs: History Is it true that you can die from eating Mentos and drinking Coke at the same time? Does Coca-Cola taste different in different countries? Does Coca-Cola contain cocaine?