Thank you for your question. We can ensure that you eating durian and drinking Coca-Cola at the same time do no harm to your health. Related Items FAQ More on Journey Is it true that you can die from eating Mentos and drinking Coke at the same time? Does 4-MEI cause cancer? Coca-Cola FAQs: Drinks What happens one hour after drinking a can of Coke?/ What happened after drinking Coca-Cola? Are there any additives in Coca‑Cola?